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Scientific Name:
Styphnolobium japonicum, syn. Sophora japonica
Family Name:
Fabaceae
Common Name:
Sophora japonica, Japanese sophora
Evidence of Activity
Pharmacokinetics (ADME)
A hybrid-hydrogel formulation of quercetin exhibited significantly greater bioavailability, solubility, and stability in healthy volunteers (N=16) relative to unformulated quercetin extracted from Sophora japonica after single-dose oral administration. Joseph 2022
Developed and validated an LC-MS method for quantitative determination of matrine, oxymatrine, sophocarpine and oxysophocarpine from Sophora japonica in dog's plasma using monocrotaline as an internal standard. [Article in Chinese] Liu 2012
Developed a method to differentiate urinary cell types using lectin staining. S. japonica agglutinin, in combination with Erythrina cristagalli agglutinin, differentiated between nucleated cells of the proximal tubules, distal tubules, collecting ducts, and lymphocytes in urine. Grupp 2001
History of Record
ORIGINAL RESEARCH BY: Oren Rabinowitz, MSc
October 2020
LATEST UPDATES BY: Antonia Kaz
March 2023