Consumption of chamomile tea containing apigenin-7'-O-glucoside resulted in the peak plasma concentration of apigenin-4'-glucuronide occurring at 2 h, with urinary excretion equivalent to 34% of intake, in human subjects.
Borges 2022
Scientific Name:
Matricaria chamomilla (syn. M. recutita, Chamomilla recutita)
Family Name:
Asteraceae/Compositae
Common Name:
German chamomile, blue chamomile
Evidence for Efficacy (Human Data)
Evidence of Activity
Other Information
Safety Data
Formulas/Blends
Dynamic Updates
Evidence of Activity
Pharmacokinetics (ADME)
Analysis of the metabolic profile changes of a combination of 9 herbal extracts, including chamomile, following in vitro digestion found the majority of the constituents to be stable against the simulated conditions, potentially reaching the colon intact.
Thumann 2020
A pharmacokinetic study found the maximum concentrations of quercetin, luteolin, and apigenin following oral administration of Matricaria chamomilla extract to be 0.29 ± 0.06 µg/ml, 3.04 ± 0.60 µg/ml, and 0.42 ± 0.10?µg/ml, respectively, in rats.
Dong 2017
An in vitro study was conducted to obtain information on which components of volatile oils or minerals are able to pass through membranes under different conditions. The transfer of chamomile oil was faster to buffer pH=1.1 than from buffer pH=1.1 to buffer pH=7.5.
Szentmihályi 2001
History of Record
ORIGINAL RESEARCH BY: Soaring Bear, Ph. D.
1998
MAJOR REVISION BY: Michael C. Tims
June 2001
LATEST UPDATES BY: Pavel Axentiev, MS
March 2023