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Scientific Name:
Matricaria chamomilla (syn. M. recutita, Chamomilla recutita)
Family Name:
Common Name:
German chamomile, blue chamomile
Evidence of Activity
Literature Reviews
A review includes Matricaria chamomilla among botanicals from the Northern Hemisphere most widely used in the care of wounds. Albahri 2023
An umbrella review of evidence-based recommendations for periodontal self-care in periodontally healthy orthodontic patients with fixed appliances found chamomile to have proven antimicrobial properties, with herbal-based mouthwashes being comparable to chlorhexidine without the side effects. Di Spirito 2023
An article presents a review of medicinal plants based on their historical usage, including Matricaria chamomilla, as well as their constituents as potential therapeutic agents against oral infectious diseases. Kováč 2022
The article presents a scoping review of the botanical characteristics, traditional uses, chemical constituents, and pharmacological activities, as well as toxicity and quality control studies of chamomile (including Matricaria chamomilla and Chamaemelum nobile), highlighting the presence of anticancer, anti-infective, anti-inflammatory, antithrombotic, antioxidant, hypolipidemic, hypoglycemic, antihypertensive, antidepressant, neuroprotective activities, among others. Dai 2022
A review provides a discussion of recent discoveries in the therapeutic applications of chamomile (M. chamomilla). Sah 2022
A literature review suggests that plants such as chamomile may improve fertility in women with polycystic ovary syndrome. Manouchehri 2022
A systematic review of complementary and alternative medicine studies identified chamomile tea among the natural products that have shown effectiveness for glycemic control in diabetes mellitus. Setiyorini 2022
A review sums up the pharmacological mechanisms potentially responsible for the antidepressant- and anxiolytic-like effects of chrysin, a flavonoid found in found in chamomile (Matricaria chamomilla). Rodríguez-Landa 2022
An article provides a comprehensive review of the ethnomedicinal uses, chemistry, and pharmacological activities of chamomile (M. chamomilla). El Mihyaoui 2022
An article reviews the pharmacological activities of α-bisabolol, one of the main active constituents of Matricaria chamomilla, with demonstrated anticancer, antinociceptive, neuroprotective, cardioprotective, and antimicrobial properties. Eddin 2022
An article examines the evidence for pro-oxidant, as well as antioxidant effects of apigenin, a major chamomile compound, in cancer cells. Oyenihi 2022
A review of evidence for the use of plant products in periodontal diseases indicates the usefulness of chamomile flowers. Gościniak 2021
A review discusses the potential use of chamomile in the treatment of sleep disorders associated with Alzheimer's disease. Marde 2021
An article reviews the evidence for the mechanisms of antispasmodic activity of several medicinal plants, including Matricaria chamomilla. Rauf 2021
A review summarizes the evidence for the potential of chamomile (Matricaria chamomilla) in the treatment of obesity and related metabolic disorders. Bayliak 2021
A literature review found apigetrin (apigenin-7-O-glucoside) found in Matricaria chamomilla to have antioxidant and anti-inflammatory properties, applicable to the treatment of upper respiratory infections, otitis media, and inflammatory disorders, as well as a neuroprotective potential. Patel 2021
A narrative review of the safety and effectiveness of herbal products most commonly used for treating sleep disorders includes chamomile among the other botanicals. Lelli 2021
A survey of information available via popular websites on complementary and alternative treatments of dry eye disease identified chamomile eye wash among the most commonly promoted therapies. Rapata 2021
An article lists chamomile among available options to treat antipsychotic-induced prolactinemia, citing limited data supporting the use. Rusgis 2021
A review of traditional medicinal Egyptian flora with a focus on cancer therapeutics listed Matricaria chamomilla among the plant species with clinically demonstrated anticancer activities. El-Seedi 2020
A review of popular remedies for the treatment of central centrifugal cicatricial alopecia, a type of alopecia that commonly affects women of African descent, found chamomile oil among the various ingredients used; however, no clinical trials were identified. Ezekwe 2020
A systematic review of pharmacological and clinical evidence identified chamomile among effective treatments of vaginal atrophy in menopausal women. Rashidi Fakari 2020
A systematic review of randomized controlled trials identified Chamomilla recutita tea and ointment among topical interventions potentially effective against intravenous therapy-related phlebitis. Goulart 2020
A systematic review of randomized controlled trials identified chamomile, among other herbal interventions, as an acute treatment for migraine. Lopresti 2020
A study provides an overview of the data on the mycotoxin contamination of medicinal plants and herbs (including chamomile). Altyn 2020
A systematic review of animal and human studies found chamomile (Matricaria recutita) to significantly improve renal and hepatic complications, oxidative stress, and dyslipidemia, associated with diabetes mellitus. Hajizadeh-Sharafabad 2020
A review of traditional European medical literature and published trials found good evidence for the use of Matricaria recutita to alleviate oral mucositis and gingivitis. Buentzel 2020
Chamomile essential oil showed complete repellency against Anopheles spp. mosquitoes (acting as potential malaria vectors), according to a review. Asadollahi 2019
A review of natural skin-whitening and anti-aging agents lists a Chamomile extract among those substances that have been shown to affect melanin synthesis. Zaid 2019
A scoping review of the evidence of health benefits of herbal teas, including chamomile, focused on the effects of these plant preparations on female health, diabetes, heart disease and weight loss. Poswal 2019
A systematic review of herbal treatments of skin diseases in dogs found evidence of wound-healing properties of chamomile (Matricaria chamomilla), as well as anti-inflammatory and other beneficial effects on healthy skin. Tresch 2019
A review identified chamomile (Matricaria chamomilla), as well as its constituent matrine, among the medicinal plants that have demonstrated beneficial effects in animal models of chemotherapy-induced peripheral neuropathy. Oveissi 2019
A review of evidence for plant-derived medicinal products for the treatment of oral mucosal lesions (such as leukoplakia and oral lichen planus) gave a special emphasis to chamomile. Salehi 2019
A review includes data on the antigenotoxic potential of chamomile. López-Romero 2018
A review of preclinical and clinical evidence found significant effects, both in humans and animals, of Matricaria recutita as a treatment of oral mucositis. Gomes 2018
An evidence-based review discusses the use of chamomile, among other complementary and alternative medicine therapies, for the treatment of acne and rosacea. Kallis 2018
A review of evidence on the effectiveness and safety of Iranian medicinal herbs identified Matricaria chamomilla among the plants that may alleviate symptoms of premenstrual syndrome. Maleki-Saghooni 2018
A review of studies on herbal and botanical remedies includes evidence that chamomile may offer relief to patients with anxiety. Malone 2018
A systematic review of preclinical and clinical evidence on GABA-modulating phytomedicines for anxiety identified chamomile among ten herbs that have been shown to interact with the GABA system in preclinical investigations, in addition to human clinical trials. Savage 2018
A review of traditional Persian medical literature identified Matricaria chamomilla among the plants used for blood clot management, as well as possessing backing from modern antithrombotic studies. Memariani 2018
A review of the biological activities of plant oils in topical skin applications, such as antioxidant and anti-inflammatory effects, promotion of wound healing, and skin barrier repair, identifies such evidence on German chamomile oil. Lin 2017
Apigenin, a flavonoid found in chamomile, reduces cancer cell glucose uptake and inhibits remodeling of the extracellular matrix, angiogenesis, and cell adhesion, according to a review of recent mechanistic studies. Kowalczyk 2017
A review of dietary strategies for the management of chronic inflammatory bowel disease identified chamomile as a promising treatment in mild ulcerative colitis. [Article in Danish] Hvas 2017
A review of human trials identified Matricaria chamomilla among supplements beneficial for ulcerative colitis. Khan 2017
The pharmacokinetics and drug-drug interactions of apigenin, a key chamomile compound, are reviewed. Tang 2016
The knowledge of therapeutic and pharmacological effects of Matricaria chamomilla (chamomile) is reviewed. Miraj 2016
Focal therapy is also not chamomile tea : Comment on Apfelbeck et al.: "Focal therapy of prostate cancer in Germany". [Article in German][No abstract] Wirth 2016
Cosmetic use of chamomile, as a "paradigmatic" cosmeceutical product, is reviewed. Milam 2016
The antilisteriosis properties of German chamomile and other Italian medicinal plants were reviewed. Rafieian-Kopaei 2015
The evidence of anti-aging cosmetic effects of cream formulations containing extracts of Matricaria chamomilla, along with other botanicals, is reviewed. Jadoon 2015
Data on the effectiveness and safety of commonly used plant-based sleep therapeutics, including chamomile, are reviewed. Yurcheshen 2015
The therapeutic potential of apigenin against breast cancer is summarized, based on in vitro and in vivo studies. Nabavi 2015
Potential benefits of chamomile tobacco-induced mucosal pathologies are reviewed. [Article in Polish] Kedziora 2015
A review of natural products with hepatoprotective activity, including chamomile, is presented. Madrigal-Santillán 2014
The mechanisms of the putative skin wound-healing activity of chamomile are reviewed. Pazyar 2014
Preclinical and clinical evidence supports an antidepressive action of chamomile, along with six other herbs, according to this review. [Article in Polish] Szafrański 2014
I've read that chamomile tea is a sleep aid--is that true? [No abstract] [No authors listed] 2013
The evidence of beneficial effects of chamomile on inflammatory skin conditions, including clinical data, is reviewed. Dohil 2013
The evidence of the potential of Matricaria chamomilla for neuroprotection and as a therapy for chemotherapy-induced neuropathy was reviewed. Schröder 2013
Matricaria recutita is one of a number of herbs with evidence of anxiolytic activity, according to this review article. Sarris 2013
Epidemiological evidence of anti-inflammatory effects of Matricaria recutita, along with Olea europaea, Vitis vinifera, and Camellia sinensis, was critically reviewed. Dell'Agli 2013
The known effects of apigenin, a flavonoid, of which chamomile is one of the two major sources (along with parsley), on gastrointestinal cancers are reviewed. Lefort 2013
Chamomile is listed among complementary and alternative medicinal agents that have at least some evidence potentially substantiating their use in dermatological surgery. Reddy 2013
The evidence of beneficial effects of chamomile, among other plants and their constituents, for oral health was reviewed. Varoni 2012
Chamomile is listed among the most important plants with digestion-enhancing properties, based on the analysis of traditional data and possible biological mechanisms. Valussi 2012
Use of chamomile in dentistry is reviewed. Taheri 2011
The medicinal uses, botany, cultivation techniques, chemical constituents, pharmacological properties, as well as biotechnological and commercial aspects of Matricaria chamomilla and its essential oil are briefly reviewed. Singh 2011
History of Record
June 2001
March 2023