A study of molecular pathways involved in the biosynthesis of α-bisabolol in German chamomile (M. recutita) identified farnesyl diphosphate synthase and α-bisabolol synthase as the key enzymes in the sesquiterpenoid production, regulated by a series of transcription factors including WRKY, AP2, and MYB, with the highest expression levels at the ray floret extension phase. Tai 2023

A study characterized the mitochondrial genome variation in 13 cultivated accessions of Matricaria chamomilla. Ruzicka 2020

A study presents a detailed account of the methodology for the identification of Matricaria chamomilla using a portable qPCR system, that should replace the traditional botanical identification procedure based on morphological and chemical properties of the plant. Yang 2020

An article reviews the work of Indian scientists at producing novel plant breeds of medicinal and aromatic crops, such as enhancing and modifying essential oil formation in Matricaria recutita, by way of gamma irradiation-induced mutations. Lal 2020

A study identified 3 sesquiterpene synthase genes, McGDS1, McGDS2, and McGDS3, correlated with the amounts of (E)-ß-farnesene, germacrene D, and ß-elemene in Matricaria chamomilla essential oil. Ling 2020

A study elucidated the genetic differences between Roman (Chamaemelum nobile) and German (Matricaria recutita) chamomile related to the production of terpenoids; in addition, both species were shown to be closely related to Chrysanthemum nankingense. Tai 2020

Analysis of volatile compound profiles showed that the main volatile compounds in German chamomile (Matricaria recutita) are terpenoids, while those in Roman chamomile (Chamaemelum nobile) are esters. Tai 2019

A PCR method of DNA-based authentication of raw and processed chamomile (Matricaria chamomilla) materials was developed, achieving the probability of identification greater than 0.9. Lu 2019

A genotyping-by-sequencing study of chamomile (Matricaria recutita) plants from identified genetic markers for flowering time and alpha-bisabolol content, with the potential to enhance breeding. Otto 2017

Genetic studies to assess self-incompatibility in six accessions of German chamomile (Matricaria recutita) were conducted. The cultivar 'Degumille' was selected as the most promising for the maintenance of self-incompatibility in chamomile. Faehnrich 2016

Expression of a (E)-β-farnesene synthase gene in Matricaria recutita was induced by methyl jasmonate treatment of the plants. A cDNA clone of the gene was obtained. Su 2015

The cDNA of farnesyl pyrophosphate synthase, a key enzyme in the biosynthesis of isoprenoids, was cloned from Matricaria recutita. The enzyme positively responded to methyl jasmonate treatment. Su 2015

A comparative cytogenetic study of the autotetraploid breed of Matricaria chamomilla and M. inodora was performed. Species-specific idiograms were composed, taking into account polymorphous variants of DAPI-banding images. [Article in Russian] Samatadze 2014

Full-length cDNA sequence of heat shock protein 90 (Hsp90) gene from Matricaria recutita was obtained and compared to other plant species. Ling 2014

The reaction mechanism of MrTPS2, a triquinane-forming sesquiterpene synthase from chamomile [Matricaria recutita] was elucidated. Hong 2013

Five terpene synthases in Matricaria recutita are characterized. Irmisch 2012

A review on chromosome counts in Tripleurospermum Sch.(20 taxa), Anthemis (1 sp.) & Matricaria (3 taxa) of tribe Anthemideae (family Asteraceae) showed that chromosome numbers of these taxa are 2n = 2x = 18, 3x = 27 & 4x = 36. Differences in ploidy level & stomatal length were also studied. Inceer 2010

Karyotypes of 3 cultivars of chamomile were studied using developed G-like banding technique. G-banding patterns of chromosomes were reproducible & chromosome-specific. Visual analysis revealed from 5 to 10 G-positive bands and/or blocks of adjacent bands on individual chromosomes. Muravenko 1999

Alcoholic extract of Matricaria chamomilla added during the early stage of Poliovirus development inhibits cellular and viral RNA synthesis [Article in French] Vilagines 1985