The American Botanical Council (ABC) is passionate about helping people live healthier lives through the responsible use of herbs and medicinal plants. As an independent, nonprofit education organization, ABC is dedicated to providing accurate and reliable information for consumers, healthcare practitioners, researchers, educators, industry and the media.
Please enjoy this information on milk thistle made available through the generosity of Euromed’s adoption.


Silybum marianum is a member of the daisy family (Asteraceae) and is native to the Mediterranean.
Formulations made with milk thistle seed are used to address biliary digestive complaints, toxic liver damage, and supportive treatment in chronic inflammatory liver disease and hepatic cirrhosis.
Additional ABC MilkThistle Resources
Milk thistle monograph from The ABC Clinical Guide to Herbs.
Milk thistle fruit monograph from Herbal Medicine: Expanded Commission E Monographs.
Milk thistle fruit monograph from The Complete German Commission E Monographs—Therapeutic Guide to Herbal Medicines.
HerbClip reviews
Effect of Milk Thistle Extracts and Isolated Constituents on CYP3A Enzyme Activity, HC# 111354-493, March 31, 2014
Pharmacokinetics and Antioxidant Activity of Silymarin Flavonolignans. HC# 111363-493, March 31, 2014
Silymarin Modulates Immune Markers in Patients with β-thalassemia Major. HC# 061363-484, November 15, 2013
Hepatitis C Interferon Treatment Non-responder Patients also Do Not Respond to Milk Thistle (60% Silymarin) Treatment. HC# 081231-456, September 14, 2012
Milk Thistle Flavonolignan Plasma Levels Greater in Patients with Non-alcoholic Fatty Liver Disease than in Those with Hepatitis C. HC# 111162-443, February 29, 2012
Silymarin's Molecular Targets for Cancer Treatment and Prevention: a Review. HC# 021026-404, July 15, 2010
Intravenous Silibinin Is Clinically Proven Effective in the Treatment for Chronic Hepatitis C Non-responsive to Standard Antiviral Combination Therapy. HC# 021022-402, June 15, 2010
Oral Silymarin Is Proven Effective in β-Thalassemic Major Patients under Conventional Chelation Therapy. HC# 021024-401, May 31, 2010
Silymarin Enhances Symptomatic Improvements in Acute Hepatitis. HC# 070591-382, August 14, 2009
Milk Thistle: Review for Veterinary Medicine. HC# 120322-230, April 15, 2003
Review of Milk Thistle Extract for Liver Therapy. HC# 062391-168, January 15, 2000
Read the press release on Euromed's adoption of Milk Thistle.
Contact us for more information on ABC's Adopt-an-Herb Program.